Anti-IRS4 antibody [EP907Y] ab52622 from Abcam

Product Specs
ItemAnti-IRS4 antibody [EP907Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab52622
Antibody TypePrimary
ClonalityMonoclonal
IsotypeIgG
Quantity10 UL, 40 UL, 100 UL
CloneEP907Y
HostRabbit
ApplicationsFlow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
Conjugate/TagUnconjugated
Gene NameIRS4
ReactivityHuman
TargetIRS4

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Long Noncoding RNA LINC00173 Promotes the Malignancy of Melanoma by Promoting the Expression of IRS4 Through Competitive Binding to microRNA-493Cancer Management and ResearchMay 5, 2020Fan Yang, Pengzhen Lei, Weihui Zeng, Jianwu Gao, Na WuDetection Kit (GE Healthcare Life Sciences, Chalfont, UK). The primary antibodies included IRS4 (cat. # ab52622; 1:500; Abcam, Cambridge, MA, USA), Bcl-2 (cat. # ab182858; 1:500; Abcam), BAX (cat. # ab32503; 1:500;

(2) Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathwayTheranosticsJanuary 1, 2018Li X, Zhong L, Wang Z, Chen H, Liao D, Zhang R, Zhang H, Kang T.p-p70S6KThr389(9234), p-4EBP1Thr37/46(2855) and HA(3724) were obtained from Cell Signaling Technology. Anti-IRS4 (ab52622) and CK1γ2 (GTX33123) were purchased from Abcam and GeneTex, respectively. Antibodies against GAPDH

(3) Downregulation of miR-493 promoted melanoma proliferation by suppressing IRS4 expressionTumor BiologyMay 6, 2017Aili Cui, Zhehu Jin, Zhonggao Gao, Mingji Jin, Lianhua Zhu, Lianhua Li, Chenglong Jin, Yinghua An(Millipore, Billerica, MA, USA). The membranes were immunoblotted with the following antibodies: anti-IRS4 (ab52622; Abcam, 3 Cui et al. Figure 1. Expression of miR-493 in human melanoma cell lines and tissues.

(4) Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijackingNature geneticsJanuary 1, 2017Weischenfeldt J, Dubash T, Drainas AP, Mardin BR, Chen Y, Stütz AM, Waszak SM, Bosco G, Halvorsen AR, Raeder B, et al.according to Sotillo et al93. Anti-IRS4 antibody used was purchase from Abcam (clone EP907Y - Product code ab52622, 1DegreeBio ID: 1DB-001-0001145254). Mouse experiments 1 million transduced HCC15 cells were suspended

(5) Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylationThe Journal of biological chemistrySeptember 19, 2014Homma Y, Kanno S, Sasaki K, Nishita M, Yasui A, Asano T, Ohashi K, Mizuno K.

(6) A novel transcript is up-regulated by fasting in the hypothalamus and enhances insulin signallingJournal of neuroendocrinologyMarch 1, 2013B Chai, J-Y Li, D Fritze, W Zhang, Z Xia, M W Mulholland

(7) The t(X;6) in subungual exostosis results in transcriptional deregulation of the gene for insulin receptor substrate 4International journal of cancerJanuary 15, 2011Fredrik Mertens, Emely Möller, Nils Mandahl, Piero Picci, Antonio R Perez-Atayde, Ignace Samson, Raf Sciot, Maria Debiec-Rychter

(8) The t(X;7)(q22;q34) in paediatric T-cell acute lymphoblastic leukaemia results in overexpression of the insulin receptor substrate 4 gene through illegitimate recombination with the T-cell receptor beta locusBritish journal of haematologyFebruary 1, 2009Kristina Karrman, Eigil Kjeldsen, Carin Lassen, Margareth Isaksson, Josef Davidsson, Anna Andersson, Henrik Hasle, Thoas Fioretos, Bertil Johansson

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Anti-IRS4 antibody [EP907Y] from Abcam

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Anti-IRS4 antibody [EP907Y] from Abcam

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